Restylane® vs. JUVÉDERM®: What’s the Difference?

Woman with beautiful skin and defined features touching her face with her hand (model)

Dermal fillers are a go-to solution for many people seeking to minimize wrinkles, replace lost volume, and create more defined facial contours. As dermal fillers have risen in popularity, hyaluronic acid-based filler manufacturers Restylane and JUVÉDERM continue developing products tailored to treat all areas of the face.

It Starts With Hyaluronic Acid

Hyaluronic acid is naturally found in the body to add volume and smooth out wrinkles. It attracts and retains moisture, providing hydration and plumping effects to the skin. Unlike biostimulator fillers such as Sculptra®, HA fillers can be reversed. While Restylane and JUVÉDERM share this ingredient, there are nuanced differences in their formulations and applications.

Restylane® Kysse vs. JUVÉDERM® VOLBELLA Lip Fillers

Lip augmentation is a popular reason for people to get fillers. Both Kysse and VOLBELLA are approved by the FDA for lip enhancement and produce results typically lasting up to 12 months or more. However, there are subtle differences in their formulations and performance.

Restylane Kysse

Restylane’s XpresHAn Technology™ is designed to provide enhanced flexibility and natural movement, making it an ideal choice for individuals seeking soft, pliable lips. The filler integrates seamlessly with the lip tissue, producing expressive and natural-looking results. Another lip enhancement filler option is Restylane Silk, which also reduces the appearance of fine lines around the mouth.


JUVÉDERM’s proprietary VYCROSS® technology used in formulating VOLBELLA creates a smoother gel consistency than Kysse. This results in subtle yet noticeable enhancement with minimal swelling or bruising. JUVÉDERM VOLBELLA is also available in different formulations, allowing practitioners to tailor the treatment to each patient’s unique anatomy and aesthetic goals. We also use JUVÉDERM Ultra XC and VOLLURE for lip enhancement.

Our previous blog post, “What Is the Best Lip Filler,” includes more information about JUVÉDERM and Restylane lip fillers.

Restylane vs. JUVÉDERM for Under Eyes

If you have dark circles under the eyes, the cause is often shadowing caused by volume loss. This creates “tear troughs” that start at the inner corner of the eye and form a half-circle hollow beneath it. Dermal fillers can eliminate the appearance of dark circles under the eyes that can make you look tired.

Both Restylane and JUVÉDERM have less viscous fillers specifically formulated for under-eye treatments such as Restylane-L, Restylane Eyelight, and JUVÉDERM VOLBELLA XC. Choosing experienced, qualified injectors for the delicate area under the eyes is essential, since injecting at the wrong depth can cause complications.

Restylane vs. JUVÉDERM for Cheek Augmentation

Whether you want to replenish age-related volume loss in the cheeks or create more defined cheekbones, fillers produce excellent results. Restylane and JUVÉDERM have long-lasting fillers approved by the FDA to lift and contour the cheeks. Restylane® Lyft and JUVÉDERM® VOLUMA add structure and support to this area, both with results that can last up to 2 years..

Ultimately, the choice between Restylane and JUVÉDERM fillers boils down to individual preferences, anatomical considerations, and the expertise of the injector. Our expert injectors at White Orchid Spa in Vero Beach, FL, create consistently excellent results using fillers. Request a consultation using the online form or call our med spa at (772) 231-1133 to schedule an appointment.

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