PRFM Hair Restoration: How Does It Compare?

Woman with beautiful blonde hair (model)

Hair restoration options for women and men consistently point to platelet-rich fibrin (PRF) treatments as one of—if not the—best. Also called platelet-rich fibrin matrix (PRFM) hair restoration, this innovative, nonsurgical procedure provides quality, long-lasting results.

How does it compare against the more well-known platelet-rich plasma (PRP) treatment or other surgical and nonsurgical options? Read on to learn more.

What Is Platelet-Rich Fibrin?

Platelet-rich fibrin consists of platelets, leukocytes (white blood cells), stem cells, and growth factors. This protein matrix stimulates hair follicle growth, replenishing areas of hair loss or thinning with thicker, healthier, and more youthful-looking scalp coverage.

In PRF hair restoration treatments, the patient’s own PRF is used to reinvigorate the scalp.

Our PRF Hair Restoration Procedure

Your PRF hair restoration treatment begins with a blood sample. One of our advanced registered nurse practitioners (ARNPs) will draw a small amount of blood from your arm and then extract the PRF using an FDA-approved centrifuge.

Once the local anesthetic has numbed your scalp, the ARNP will begin injecting the PRF to fortify areas of thinness and replenish areas of baldness. The procedure generally lasts 45 to 60 minutes and requires no downtime afterward.

Most med spa guests will receive 4 monthly treatments in their initial hair restoration therapy regimen. In the 12-month period that follows, we encourage guests to schedule a maintenance treatment every 3 months to continue stimulating the scalp and enhancing the results.

After reaching the one-year mark, the maintenance schedule will vary depending on your unique goals.

Patients who can’t produce sufficient PRF or prefer an alternative can benefit from our AnteAGE® microneedling hair treatments instead. This robust solution is derived from bone marrow and contains both cytokines and growth factors to achieve similar regenerative results.

You can learn more about PRF and AnteAGE® in our related blog post.


PRF is the next generation of platelet-rich plasma (PRP) hair restoration treatments. PRP creates a serum from the patient’s platelets, while PRF stabilizes this into a gel-like consistency by adding the fibrin matrix.

PRF is more concentrated than PRP and contains more bio-stimulating components, giving it an edge over its predecessor.

PRF vs. Microblading

Med spa guests who are concerned by the signs of a receding hairline may be good candidates for a microblading treatment. One of our Brow & Lash specialists will “tattoo” the skin with semi-permanent pigment to add color and realistic hair-like strokes.

Although unsuitable for covering large areas, microblading can create the appearance of hairline fullness until a more intensive treatment such as PRF is required.

PRF vs. Hair Transplants

A surgical hair transplant procedure removes small areas of hair-bearing skin and relocates them to balding or thinning areas. The treatment typically spans multiple surgeries to create gradual, natural-looking results and requires months for the skin to heal and the grafts to settle into their new positioning.

The American Society of Plastic Surgery details other surgical hair restoration options, including flap surgery and scalp reduction, which are more aggressive but offer near-immediate results.

PRF, by contrast, is minimally invasive and requires no downtime. Although it takes time for the improvements to appear, the end result is naturally fuller (and fully natural!) hair regrowth.

Get Started

If hair loss is making you self-conscious, PRF can help. Please request a consultation or call us at  (772) 231-1133 to take the next step toward healthy hair restoration.

Leave a Reply

Fields marked with * are required.


Did you know we offer two-way texting?

Text (772) 231-1133 for a more immediate response!